Hearty Meat Pizza Casserole

Featured in Hot, bubbly pizza from your oven.

This casserole puts pizza and pasta in one tasty pan. Begin with flavorful ground beef, sausage, and pepperoni in herbed tomato sauce. Cover with gooey cheese and a layer of pizza dough brushed with oil and sprinkled with herbs and cheese. Once baked, it turns crispy and golden while staying hearty inside. Great for sharing or enjoying leftovers.
alicia in the kitchen
Updated on Sun, 13 Apr 2025 14:12:58 GMT
Hearty Meat Pizza Casserole Pin it
Hearty Meat Pizza Casserole | tasteofsavor.com

This stick-to-your-ribs combo of pizza meets casserole creates the ultimate meat enthusiast's treat. I whipped this up for a community dinner once, and now it's the #1 dish folks ask me to bring, mixing everything great about pizza with the down-home feel of a family casserole. The taste reminds me of my neighborhood pizza joint, but with that special touch only homemade food delivers.

Through years of family get-togethers, this dish has become our favorite comfort meal. When those cheese strings stretch from pan to plate and that smell fills up the house, everyone shows up in the kitchen before the timer even dings.

Key Ingredients Breakdown

  • Ground beef: Go with 85% lean for good taste without swimming in grease. Pick fresh meat with a vibrant red color
  • Italian sausage: Real pork sausage brings amazing flavor. Go mild or spicy based on what you like
  • Pepperoni: Grab quality, thicker slices for better bite and stronger taste
  • Mozzarella cheese: Shred it yourself for the creamiest melt. Skip the bagged stuff for best results
  • Pizza sauce: Choose a hearty tomato basil type for real pizza flavor and nice thickness

Putting It All Together

Getting The Oven Ready:
First, heat your oven to 425°F. The hot temperature will give you that awesome crispy top and melty cheese. While it warms up, give your 9x13 baking dish a good spray with cooking spray, getting the sides too.
Cooking The Meats:
Put a big skillet on medium-high heat. Throw in the ground beef and sausage together, breaking it up as it cooks. Keep going until you don't see any pink, usually about 8-10 minutes. Then drain off the extra fat so your dish won't end up greasy.
Boosting The Taste:
Toss in your chopped pepperoni with the cooked meat. Sprinkle flour and Italian seasoning over everything, stirring the whole time so it doesn't clump. This step makes a rich base that helps thicken everything up nicely.
Making The Sauce:
Pour in the tomato basil sauce and mix it with your seasoned meat blend. Let it bubble gently, giving the flavors time to mix and the sauce time to thicken a bit. This takes around 5 minutes.
Layering Everything:
Dump the meat sauce mix into your greased baking dish and spread it out evenly. Cover it completely with a thick layer of mozzarella. Then carefully roll out the pizza dough on top, gently pulling it to reach all the edges.
Simple Meat Lovers Pizza Casserole Pin it
Simple Meat Lovers Pizza Casserole | tasteofsavor.com

My Nonna always told us to wait before cutting into casseroles. This little bit of patience lets everything firm up so you won't get runny filling all over your plate when you serve it.

What To Serve With It

Dish up this filling casserole with a fresh Caesar salad and some buttery garlic bread. For a full dinner, add some roasted veggies on the side. A nice glass of bold red wine goes perfectly with all these rich flavors.

Switch It Up

  • Make it your own by adding some cooked mushrooms, sweet caramelized onions, or colorful roasted peppers between the meat and cheese
  • Play with different cheeses like provolone or fontina
  • Put some fresh basil leaves under the pizza dough for an aromatic twist

Storing Leftovers

Store any extra portions covered in your fridge for up to 4 days. When it's time to eat again, warm single servings in a 350°F oven for about 15 minutes to keep the top crispy. Try not to use the microwave as it'll make the crust go soft.

Tasty Meat Lovers Pizza Casserole Pin it
Tasty Meat Lovers Pizza Casserole | tasteofsavor.com

This meat lovers pizza casserole has turned into my trademark dish for group meals, getting tons of compliments and recipe requests every time I make it. The mix of three different meats, stretchy cheese, and that crispy top makes an irresistible comfort food that brings the whole gang together. It just goes to show sometimes the tastiest dishes come from mashing up two foods everybody already loves.

Frequently Asked Questions

→ Can I make this dish in advance?
Sure! Prepare the meaty base early, but don’t add the pizza crust until you're ready to bake.
→ What can I use instead of pizza dough?
Crescent roll or biscuit dough works nicely as a quick swap for the crust.
→ Can I include veggies?
Absolutely! Toss in sautéed peppers, mushrooms, or onion for more flavor and an added healthy touch.
→ How do I store leftovers?
Keep it sealed in the fridge for up to 3 days. Reheat in the oven to get that crust crispy again.
→ Can this dish be frozen?
Yes, freeze it without the crust for up to 3 months. Add a fresh crust when it's baking time.

Meat Lovers Pizza Casserole

A rich dish packed with three tasty meats, a savory tomato base, melty cheese, and topped with a golden pizza crust.

Prep Time
15 Minutes
Cook Time
25 Minutes
Total Time
40 Minutes
By: Alicia

Category: Pizza

Difficulty: Intermediate

Cuisine: Italian American fusion

Yield: 8 Servings

Dietary: ~

Ingredients

→ Protein Choices

01 1 cup chopped pepperoni, small pieces
02 1 pound pork sausage
03 1 pound ground beef, lean

→ Flavors & Sauce

04 4 teaspoons, split, of Italian herb mix
05 1 (26-ounce) jar basil-tomato pasta sauce
06 1/4 cup plain flour to thicken sauce

→ Topping & Crust

07 1 (13.8-ounce) tub of ready-to-roll pizza dough
08 3 tablespoons freshly grated Parmesan
09 2 cups mozzarella, shredded, split in two
10 1 tablespoon olive oil for brushing on crust

Instructions

Step 01

Set your oven to 425°F and lightly grease a 9x13-inch baking dish with cooking spray before starting.

Step 02

In a large pan over medium-high heat, cook the sausage with the ground beef until there's no pink left. Drain off any fat so it won’t affect your dish's texture.

Step 03

Toss your cooked meats back in the skillet with the pepperoni, flour, and 3 teaspoons of the Italian seasonings. Stir in the pasta sauce and let it bubble gently.

Step 04

Pour the saucy mixture into your baking dish, covering it with 1 and 1/2 cups of mozzarella. Unroll the pizza crust on top for the next layer.

Step 05

Coat the pizza dough with olive oil, then sprinkle the rest of the seasoning, mozzarella, and Parmesan on top. This creates a crispy, flavorful crust.

Step 06

Bake for about 20 to 25 minutes or until the crust is a beautiful golden color and the cheese is bubbling away.

Notes

  1. This cozy dish brings the joy of pizza layered in casserole style.
  2. Three types of meat make it a protein-packed meal for carnivores.
  3. The blend of mozzarella and Parmesan ensures every bite is gooey yet crispy.

Tools You'll Need

  • Large skillet
  • Baking dish (9x13-inch)
  • Spoons for stirring
  • Brush for applying oil

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Includes dairy (Parmesan and mozzarella cheese)
  • Contains gluten (pizza dough and flour)

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 520
  • Total Fat: 32 g
  • Total Carbohydrate: 28 g
  • Protein: 35 g